Human Elongator complex is involved in cell cycle and suppresses cell growth in 293T human embryonic kidney cells

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Human Elongator complex is involved in cell cycle and suppresses cell growth in 293T human embryonic kidney cells.

Elongator complex has been associated with hyperphosphorylated RNA polymerase II and is known to play critical roles in transcriptional elongation, as well as in tRNA modification and exocytosis. However, the specific mechanism of how human Elongator complex regulates cell growth and cell cycle remains unclear. To investigate the composition of human Elongator complex and its effects on cell gr...

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ژورنال

عنوان ژورنال: Acta Biochimica et Biophysica Sinica

سال: 2009

ISSN: 1672-9145,1745-7270

DOI: 10.1093/abbs/gmp072